I'd be very interested how others deal with blocking lists of known bad guys, transparent proxies etc. I know there are IP lists that can be obtained from various places, one that I recently saw has over 500k entries..
That's obviously not suitable for an edge ACL or null routing.
How do others deal with blocking very large lists of IPs, or do you just not do this?
I'd be particularly interested in solutions involving F5 BigIPs, FWSM or ASA.