Since we have enable layer 3 switching on our two 4506 switches, we have not been able to ping them. Any ideas that may help us resolve this issue.
If all you did was type 'ip routing' on the switches, you probably lost your default gateway.
With ip routing disabled, the switch relies on the 'ip default-gateway' command to see how to communicate with other networks.
Once you enable ip routing, we no longer use the 'ip default-gateway' command, but instead look in your routing table to see where to send packets.
To fix this, log into the switch and look for a command looking like this:
ip default-gateway 10.1.1.1
and convert it to this:
ip route 0.0.0.0 0.0.0.0 10.1.1.1