Yes it is possible to manage the MSFC with security manager. If you select an FWSM that has these types of changes, Security Manager notifies you that you must include the MSFC in the deployment job, and it will select the MSFC device for you automatically. However, if the MSFC is already included in another active deployment job, you cannot include the MSFC in the current deployment job. You must remove the MSFC from the other deployment job, discard the other deployment job, or include the FWSM in the other deployment job.
The following URL may help you:
http://www.cisco.net.lv/en/US/docs/security/security_management/cisco_security_manager/security_manager/3.2.1/user/guide/dppage.html#wp983106