Customer with 12 1700 switches across a WAN, that connect to a webapp served by IIS. Every Monday the remote sites have no access (404) to the Webapp, and we have to reboot the switch. The remote users can ping the server, and LAN users can access the webapp.
IIS is running, restarting it has no effect, and local users can access it.
A NetStat shows multiple connections to IIS in a TIME_WAIT state.