I've just observed a hapless Cisco consultant try to make NAC 4.1 work on computers with machine GPOs, roaming profiles, logon scripts within user GPOs, and for that matter legacy logon scripts with "run logon scripts synchronously" enabled. All of these technologies seem to fail on a NAC-enforced connection.
We assign software on machine GPOs and we use roaming user profiles, and it seems we either need to have a domain controller and profile share on the isolation VLAN, which defeats the purpose of NAC, or perform some kind of machine authentication, which can occur before GPO processing and net logons can happen.
While I'm not the Cisco consultant, it wasn't hard to recognize this problem.
Everything I've read about NAC and CAA suggests this is a per-user compliance solution and not a per-machine solution. Surely others have observed this, and I think this is what machine authentication (802.1x) NAC, as opposed to user authentication NAC, is all about. At the risk of sounding like a total n00b, where can I start researching a NAC solution that supports what I want and lets us use the Cisco NAC gear we've already invested in?