Hello Vinoth,
your question is not clear.
If you add a new site to site VPN you probably need to modify NAT configuration to avoid to translate traffic that has to be sent to the FW for encryption.
You can use PBR on receiving interface to send to firewall traffic for the new site to site VPN.
the ACL for NAT if extended has to deny traffic to the site to site VPN.
example:
central site 10.10.0.0/16
new remote site 10.100.100.0/23
access-list 121 deny ip 10.10.0.0 0.0.255.255 10.100.100.0 0.0.1.255
access-list 121 permit ip 10.10.0.
0 any
second line is for traffic to internet that has to be translated.
First line takes case of VPN traffic that is denied = not NATTED
Hope to help
Giuseppe