I've been using UCCX 8.5 on VMWare with local storage for about a year. I use VEEAM Backup to make backups of all my virtual servers. One issue I've run accross is that when VEEAM takes a snapshot of the UCCX server, the agents are logged out of Cisco Agent Desktop and get an error. I've managed to work around this by making backups run after our call center is closed (Today, however, I accidentally ran a backup and irritated the call center managers when all their users got logged out).
I've surmised from the various documents I've read that snapshots are not supported. I'm wondering how others using CCX on VMWare do their backups and if there are any clever work-arounds to this issue.