You can do this with the Get Call Contact Info step to save the calling number into a variable. Once you have that, you can evaluate it against a match statement, an XML document, or if you have premium, against a database such as your CRM system.
In the most simplistic example, you could use a match statement. Each branch of the statement would be a different calling number. Within that branch you could change the caller priority, the queue they will be placed in, or assuming that the account managers are not in UCCX, you could transfer the call to their directory number using the Call Redirect step.
If you will be changing this often I recommend investigating the external XML document or SQL database instead. This will minimize the changes to the script. Fewer changes equals fewer chances of screwing it up. :)
