I would personally suggest using an Outboud and Inbound ACL on the same interface of the ASA unless there is a very specific need for it.
You might end up complicating the setup in the long run and not necesarily gaining anything in return.
In your above decribed situation the traffic would match the Inbound ACL on the "inside" interface and the Outbound ACL on the "outside" interface. Though naturally in these ACLs the source address is different as the ASA probably does NAT for the source in between?
Hope this helps
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Table of ContentsIntroductionVersion HistoryPossible Future
UpdatesDocuments PurposeNAT Operation in ASA 8.3+ SectionsRule Types
Network Object NATTwice NAT / Manual NATRule Types used per SectionNAT
Types used with Twice NAT / Manual NAT and Network Obje...
Table of Contents Introduction:This document describes details on how
NAT-T works. Background: ESP encrypts all critical information,
encapsulating the entire inner TCP/UDP datagram within an ESP header.
ESP is an IP protocol in the same sense that TCP an...