All email-based traffic is solely sourced from Outlook 2007 client applications and there doesn't seem to be any viruses or other irregular traffic to cause this error. In fact, I have been unsuccessful in locating this error message using either the Output Interpreter or the Error Message Decoder tools.
The following is an abbreviated configlet from that router(the portion which pertains to SMTP traffic):
class-map type inspect smtp match-all smtp_dpi_class
description match SMTP application payload size
match data-length gt 75000000
policy-map type inspect smtp smtp_dpi_policy
description log SMTP information based on Payload Size
class type inspect smtp smtp_dpi_class
class-map type inspect match-all smtp_class
description match SMTP application
match protocol smtp extended
policy-map type inspect inside_to_outside
description Inside to Outside traffic policy
class type inspect smtp_class
service-policy smtp smtp_dpi_policy
All other ZBFW configuration is per best-practice, and this is the only traffic that seems to be causing issues.
All help is greatly appreciated and thanks so much for your time.
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