Hi,
This isn't something that I've done but it should be possible.
I would guess that you will not be able to create directories on the Compact flash within Slot0.
I would imagine that the CME files configured like this example.
tftp-server slot0:P00308000500.loads
tftp-server slot0:P00308000500.sb2
tftp-server slot0:P00308000500.sbn
tftp-server slot0:P00308000500.bin
Good luck.
Cheers,
Mike.