What are the challenges one may face when migrating from a 6500 to a Nexus 7000? I guess part of the answer is that it depends on where the 6500 is positioned in the enterprise. For example, if it is being used at the WAN edge with the Flex Wan module, the Nexus poses a problem because it does not support any legacy serial/OC WAN linecards. All it supports is ethernet.
On the other hand, if the 6500 is being used at the aggregartion layer of a data center and has switched modules deployed (FWSM, CSM, etc), the challenge when migrating to the 7000 will be that the 7000 does not support such modules and separate appliances must be used instead.
Is there a comprehensive overview document that anyone may know of that elaborates on such a migration in terms of a stargtegy, challenges, considerations, etc?
You've kind of covered it to be honest. The Nexus 7000 gives greater port density in terms of 10Gbps etc. but it is not equivalent to a 6500 with either FlexWAN modules or service modules. Really the Nexus is used as an aggregation/core switch where your main requirement is for 10Gbps connectivity.
The 6500 as you know is a far more flexible device and while it can't support the 10Gbps density of the 7000 it can support intergrated service modules etc. Obviously you can look to deploy standalone modules eg. the ASA 5580 has comparable throughput to the FWSM if you do not want to use 6500 switches.
Have a look at this doc if you haven't already seen it - first link from this search page -
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