I have a 7835 running over 600 translation patterns (which necessarily doesn't answer your question). The problem that has been experienced in the past has been nothing more then a browser issue. MS SQL can handle 400 Xlation patterns no problem, even on a 7825. The problem was with IE consuming 100% CPU to display the pattern when you did a "find". I'm running CM 3.2(2c) with over 600 and it works flawlessly.
Are you getting this error “Installer User Interface Mode Not Supported. The installer cannot run in this UI mode. To specify the interface mode, use the -i command-line option, followed by the UI mode identifier. The value UI mode identifiers...
The below trick might come handy when you have to add a new node to a cluster but you don't have or is unsure of the security password for the publisher. This procedure has been around for ages.
1) Login into the CLI of the Publisher.