First place you should always start when you get the failsafe message like that is the application event log. There is always an error (or errors) logged there when that message is played which should point us in the right direction.
It's probably a security issue. I've seen this error come up with the AvCsMgr process cannot query the SCM on the Exchange server for the status of the Exchange service(s). This status check is done on the Exchange server that holds the mailbox for the subscriber account when "GetMailboxStatus" is called. What account is the AvCsMgr running as, and if it's a domain account, what group membership does it have?
Are you getting this error “Installer User Interface Mode Not Supported. The installer cannot run in this UI mode. To specify the interface mode, use the -i command-line option, followed by the UI mode identifier. The value UI mode identifiers...
The below trick might come handy when you have to add a new node to a cluster but you don't have or is unsure of the security password for the publisher. This procedure has been around for ages.
1) Login into the CLI of the Publisher.