That would be the first place to start, look at uplinks for utilization problems during the problem periods . Start checking the logs of all switches during the problem periods to see if anything unusual is showing up . Check for things like spanning roots being in the wrong place . Look for any links that have a lot of errors on them . I doubt it is a switch utilization issue though it can't be ruled out as we have seen a user bury a 6500 Sup 720 . Even if its a little busy they shouldn't get timeouts, you may have to get a sniffer and look at it.