Yes. Just configure the required sigs for the action of blocking and configure the blocking through the management platform (I didn't see what it is in your case) as per the instructions on the urls provided earlier.
If you use the VMS IDSMC, and if the sensor's configs are exactly the same, then you could use the "copy config" option to replicate the config across multiple sensors.
Are you using SSH or telnet to the router for blocking? Try to do this manually from the sensor to the router, run deb ip packet on the router for just the traffic between the sensor and the router and see what you get in the deb.
access-list 101 permit ip host x.x.x.x host y.y.y.y
access-list 101 permit ip host y.y.y.y host x.x.x.x
Table of ContentsIntroductionVersion HistoryPossible Future
UpdatesDocuments PurposeNAT Operation in ASA 8.3+ SectionsRule Types
Network Object NATTwice NAT / Manual NATRule Types used per SectionNAT
Types used with Twice NAT / Manual NAT and Network Obje...
Table of Contents Introduction:This document describes details on how
NAT-T works. Background: ESP encrypts all critical information,
encapsulating the entire inner TCP/UDP datagram within an ESP header.
ESP is an IP protocol in the same sense that TCP an...