There is no difference between whatever ports are used.Its the same access list configuration to allow port 537.configuration should be done only on the email clients for the port 537 so that clients can start sending messages on port 537 instead of port 25.
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We have configured the outside and inside Interface with official ipv6 adresses, set a default route on outside Interface to our router, we also have definied a rule , which also gets hits, to permit tcp from inside Interface to any6.
In Syslog I also se...