Yes, you can map ports to the same host or different hosts internally.
> static (inside,outside) tcp 5001 smtp
> static (inside,outside) tcp 5002 2001
> static (inside,outside) tcp 5003 2002
> static (inside,outside) tcp 5004 2003
You can't map the smtp pot to more than one internal port, but as long as all your port numbers are different then you should be fine. The can also be the keyword "interface" to map them to the PIX's outside interface IP address.