Signature 4507 fires when a protocol decode of 161u traffic fails stay within the bounds of the SNMP protocol. There are some SNMP implementations that have been know to cause a false positive, however we don't know of any non-SNMP traffic causing false positives.
I would verify that SNMP isn't running on the machine, or that the user wasn't messing around with something. If you find that it is a false positive, please provide email@example.com a network trace and Cisco will correct it.
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We have configured the outside and inside Interface with official ipv6 adresses, set a default route on outside Interface to our router, we also have definied a rule , which also gets hits, to permit tcp from inside Interface to any6.
In Syslog I also se...