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Spam Blocker Site Design

Have not been able to figure out how the Cisco Spam Blocker appliance fits into the topology behind a firewall. Would appreciate any comments.

1) Can a mail server be completely isolated from the Internet with the Spam Blocker as its gateway, or does the mail server still need its own IP/DNS A records for POP/IMAP and SMTP access by authorized remote users (road warriors).

2) Can one appliance service more than one mail server? (e.g., primary and backup servers.)

TIA

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