Most of the time, 802.1x will use a radius server that is tied to AD. You can look on CCO regarding configuring 802.1x on autonomous AP or on a Unified network. There are other option in autonomous in which you can have the AP store the credentials, but now a days when users or computers are users/computers of a domain, it is much easier to use a radius server that looks up the credentials entails in AD.
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-Scott
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