What happens when you run the TMS installer as admin (right-click: run as administrator). I've had to do this on our TMS installs/upgrades, even though I'm an admin on the server. I'm not in front of my office computer, but I'll check my TMS folder properties, can you tell me specifically the folder you're talking about?
I had the same problem upgrading to 14.5.0. Even if I choose "run as administrator" it cannot remove the old version and the wizard terminated. I found that the anti-virus software caused problems (Symantec). I disabeled it and everything worked like a charm :-)
Are you getting this error “Installer User Interface Mode Not Supported. The installer cannot run in this UI mode. To specify the interface mode, use the -i command-line option, followed by the UI mode identifier. The value UI mode identifiers...
The below trick might come handy when you have to add a new node to a cluster but you don't have or is unsure of the security password for the publisher. This procedure has been around for ages.
1) Login into the CLI of the Publisher.