Definitely. You can actually restore to a machine that has a different IP address, name, domain, different drives, even a different back-end as long as its exchange-based (e.g. back up exchange 5.5 and restore on exchange 2000/2003).
Are you getting this error “Installer User Interface Mode Not Supported. The installer cannot run in this UI mode. To specify the interface mode, use the -i command-line option, followed by the UI mode identifier. The value UI mode identifiers...
The below trick might come handy when you have to add a new node to a cluster but you don't have or is unsure of the security password for the publisher. This procedure has been around for ages.
1) Login into the CLI of the Publisher.