Perhaps we had a better understanding of what you are trying to achieve we might give better advice. But based on what you have given us so far I would suggest this as a solution that would work
crypto map ABC local-address loopback1
crypto map DEF local-address loopback2
or if you really need to have just a single crypto map then my suggestion is to use the crypto map and to not configure the local-address. Then IOS will use the address of the interface through which it exits as the address for the traffic.
Table of ContentsIntroductionVersion HistoryPossible Future
UpdatesDocuments PurposeNAT Operation in ASA 8.3+ SectionsRule Types
Network Object NATTwice NAT / Manual NATRule Types used per SectionNAT
Types used with Twice NAT / Manual NAT and Network Obje...
Table of Contents Introduction:This document describes details on how
NAT-T works. Background: ESP encrypts all critical information,
encapsulating the entire inner TCP/UDP datagram within an ESP header.
ESP is an IP protocol in the same sense that TCP an...