The processing of access lists is sequential and when any line of the access list is a match then there is no more processing of the access list. Since the first line in your suggestion will deny tcp any any eq smtp there would never be any match on the second line since host 10.x.x.x would be denied on the first line.
And I am puzzled what you would see in show ip route when you try to filter it by that access list since the IP routing table has no information in it about tcp 25 (smtp). Show access-list 102 would seem to be more logical.
We are pleased to announce availability of Beta software for 16.6.3. 16.6.3 will be the second rebuild on the 16.6 release train targeted towards Catalyst 9500/9400/9300/3850/3650 switching platforms. We are looking for early feedback from custome...